Copper Peptide GHK-Cu 2:1 [Peptide]

Description Copper Peptide GHK-Cu 2:1 [Peptide] The product is only intended for laboratory research use and not for human consumption.  Available quantities: 2 mg 5mg 10mg 50mg 100mg 500mg 1000mg Product Information  Product name Copper Peptide GHK-Cu 2:1 [Peptide]   Peptide purity (HPLC)  98-99%  Molecular Formula C14H22CuN6O4 Molecular Weight 401.9 g/mol Synonyms Glycyl-L-Histidyl-L-Lysine; Growth-modulating peptide; Kollaren; Liver cell growth factor; Liver growth factor Cu-GHK; Glycyl-histidyl-lysine, monocopper salt CAS 49557-75-7 IUPAC 6-Amino-2-[[2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid Source  Synthetic  Form  Powder Shelf Life  Up to 2 years in powder form under recommended conditions  Molecular Sequence of Copper Peptide GHK-Cu 2:1 [Peptide] Gly–His–Lys Or in full N- to C-terminus notation: H–Gly–His–Lys–OH Gly = Glycine His = Histidine (primary copper-binding residue) Lys = Lysine OH = Free C-terminal carboxyl group Handling and Storage of Copper Peptide GHK-Cu 2:1 [Peptide]  The peptide compound should be stored in a cool and dry place to maximize its stability. For better storage, it is recommended to keep the Copper Peptide GHK-Cu 2:1 lyophilized peptides refrigerated between 2°C and 8°C (36°F–46°F) in an air-sealed container. Lab user exposure Redissolving Choice of container and precautions Wear laboratory coats, nitrile gloves, and eye protection.  Avoid prolonged or repeated exposure and avoid inhalation. Avoid contact with eyes or skin. The product is non-hazardous for lab-to-lab or air transportation. Handle inside standard laboratory containment. Can be reconstituted in sterile distilled water or suitable buffer solutions. A small amount of DMSO or 0.1% TFA may be used to test or improve solubility. Mix gently, avoid high-temperature heating.  Low-binding sterile polypropylene to prevent absorption. Borosilicate glass vials to prevent absorption in the glass walls.  Avoid polystyrene and lab plastic containers. Avoid amber vials or opaque containers. Overview of Product Preclinical studies have indicated that Copper Peptide GHK-Cu 2:1 is a combination of naturally occurring peptides Glycyl-L-Histidyl-L-Lysine (GHK) and copper ions. In laboratory peptide research, the term 2:1 refers to the molar ratio that includes two molecules of GHK that bind to one copper ion, forming a stable peptide-copper complex. In preclinical studies, it has been detected in plasma, saliva, and urine of research models.  Working Mechanism of Copper Peptide GHK-Cu 2:1 In cell culture studies, GHK-Cu 2:1 has been shown to increase the activity of copper-dependent enzymes in experimental models. In addition, GHK-Cu 2:1 was found to act as a copper ion carrier in laboratory models.  Lab evidence revealed that GHK-Cu 2:1 caused an increase in extracellular matrix (ECM) protein expression and reduced pro-inflammatory cytokine expression. In a few experimental models, GHK-Cu 2:1 was found to influence the expression of various genes involved in inflammation, extracellular matrix production, and oxidative stress response.  In experimental peptide research, GHK-Cu 2:1 has been observed to stimulate vascular endothelial growth factor (VEGF) expression, promoting angiogenesis in tissue-engineered constructs. Along with potential mechanisms, the compound also has some laboratory observations in preclinical settings: Cell stress Gene changes Slow growth Protein imbalance Cell shrinkage Variability observed in laboratory experiments TFA Salt Form  Copper Peptide GHK-Cu 2:1 is provided in its TFA salt form. Residual trifluoroacetate content is typically up to 10% w/w. It depends on the final formulation and lyophilization conditions. The exact TFA content can be confirmed by batch-specific COA. Disclaimer Copper Peptide GHK-Cu 2:1 peptide is intended exclusively for laboratory research purposes. RCDbio products are not intended to diagnose, treat, cure, or prevent any disease. The Food and Drug Administration has not evaluated the statements on our website. By purchasing, you agree to our Terms and Conditions. For queries, complaints, or support, please contact [email protected].